Immune-metabolic genesis of pathological processes

Melatonin as Antioxidant Under Pathological Processes

Many are the diseases which course with free radical formation. These disorders cover a great range of fields such as neurodegenerative, immune, inflammatory and mitochondrial-related diseases. Melatonin is the main pineal gland product and it functions as “time-giver” in the regulation of circadian rhythms, among others. But the actions of melatonin are not only restricted to the neuroendocrin...

Pathological Processes in Malaria and Blackwater Fever

Grammatical Formalization of Metabolic Processes

In the field of biotechnology and medicine it is of interest to model and simulate metabolic processes. The usual methods to model metabolic pathways are chemical descriptions and differential equations. Moreover, the graph theoretical aspect is discussed and the development of expert systems is in process. In this paper we present the formalization of metabolic processes. Our formalization is ...

P 60: The Effect of Melatonin as a Therapeutic Goal on Multiple Sclerosis Through Immune Processes

Multiple sclerosis is an autoimmune disease of the central nervous system which is accompanied by demyelinating the neurons. The imbalance between the T cell effectors and T cell regulators is thought to have a role in the pathogenesis of the disease. Melatonin is a hormone that is secreted by pineal gland which has an important role in circadian rhythm and immune-modulatory effects. Melatonin ...

Kinetic Aspects of Regulation of Metabolic Processes

Hysteretic enzymes are defined as those enzymes which respond slowly (in terms of some kinetic characteristic) to a rapid change in ligand, either substrate or modifier, concentration. Such slow changes, defined in terms of their rate relative to the over-all catalytic reaction, result in a lag in the response of the enzyme to changes in the ligaml level. Several mechanisms, including ligand-in...